Friday, February 24, 2012

Omega3 Fish Oil Boosts Tamoxifen Therapy in Breast Cancer

We have already discussed a study showing that women who use omega3 fish oil have fewer breast cancers.  See DrWinsett.com: Fish oil (Omega3) reduces breast cancer risk!
Now we find that in an animal model, adding fish oil intensifies the therapeutic response to tamoxifen.


Researchers lead by A Manni at Fox Chase Cancer Center in Pa studied the effects of increasing doses of fish oil with or without tamoxifen in an animal model of induced breast cancer.  They studied the protein Ki67, which is a measure of proliferation.  In a dose dependent fashion, the fish oil reduced Ki67 expression, which is linked to tumor growth and metastasis.  So tamoxifen and fish oil were additive in there beneficial effects on breast cancer tumors.


This was presented at the American Association of Cancer Research 2011 available at http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=5ef6c8c5-09dc-48c5-b601-42fac30b2b2c&cKey=bc4ad1fe-88a0-4e09-a786-6500fe4f2798&mKey=%7b507D311A-B6EC-436A-BD67-6D14ED39622C%7d.


High quality fish oil is available and is safe.  Now we may have another indication for its use.  Discuss it with your doctor.




Together we can prevent 75,000 breast cancer cases each year.

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