A great way to kick start a diet is to have a protein shake in the morning after exercise. We now have evidence for how and why the protein makes you feel full.
Recent research, published in Cell, online abstract at http://www.cell.com/abstract/S0092-8674(12)00760-X, may explain this known effect of proteins, not yet explained. It is part of the communication between gut and brain leading to that feeling of satiety after a protein meal that is explained by the new findings.
When you eat a protein meal, the proteins are broken down into peptides for absorption. It has been recently discovered that these peptides block receptors located in the portal vein, the major vein draining the gut after a meal. These receptors are called mu-opiod receptors or MOR's. Stimulating these receptors enhances food intake, but blocking them makes you feel full. Peptides block these receptors, which causes the brain to send a signal back to the gut to release glucose (gluconeogenesis), which suppresses the desire to eat. It may be that controlling this normal feed-back mechanism may lead to obesity treatment.
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This is general medical information and not personal medical advise.
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